Category Archives: Research Article

Volume 112 Issue 3, June 2026

This issue contains the following articles:
Cancer prevention and cancer avoidance: Challenges and opportunities
Choriocarcinoma: Diagnosis, treatment and management of a rare germ cell tumour. An update review
Synergistic effects of XPO1 inhibitors combined with CD19 CAR-T cells in TP53-mutated DLBCL
Diagnostic and prognostic role of GPX1 in NK/T cell lymphoma
The clinical usefulness of knowing CHRNA5 polymorphism genotype: paving the way for personalized therapy
ALYREF promotes laryngeal cancer progression through a lactate-mediated lactylation feedback loop that enhances glycolysis
Identification and selection of the best artificial intelligence methods developed for detection and diagnosis of breast cancer
Prevalence and impact of germline mutations in pancreatic ductal adenocarcinoma
Survey among childhood cancer survivors about their preferences on functionalities of a to-be-developed Survivorship Passport Mobile App

Breath analysis for non-invasive detection of breast cancer: A prospective observational cohort study

BreathBC is a multicenter prospective observational cohort study aimed at comparing metabolic profiles from exhaled breath of patients with breast cancer (BC) and malignancy-free controls. The study accounts for the novelty and complexity of breath analysis, with a particular emphasis on the standardization of each step in the process.

Survey among childhood cancer survivors about their preferences on functionalities of a to-be-developed Survivorship Passport Mobile App

Investigate preferences of childhood cancer survivors (CCS) or of their caregivers (CG) about functionalities of a to be developed mobile app intended to improve compliance with a personalized survivorship care plan (Survivorship Passport) delivered according to the PanCareFollowUp model.

Ethical challenges and multidisciplinary approaches in end-of-life oncology care: Insights from the 2025 AIOM Ethics Days

End-of-life care in oncology represents a complex and multidimensional challenge that requires ethical awareness, effective communication, and multidisciplinary collaboration. Drawing from the discussions and data presented during the 2025 AIOM Ethics Days, this paper highlights key aspects influencing the quality and humanity of end-of-life care.

The “empty speech bubbles”: Explaining cancer through play. A pediatric oncology unit pilot experience

This pilot study aimed at evaluating the feasibility and acceptability of a structured psycho-educational intervention designed to increase disease awareness in children with tumors. The primary objective was to promote psychological adjustment by supporting children’s understanding of their illness and facilitating open parent–child communication about cancer.

Identification and selection of the best artificial intelligence methods developed for detection and diagnosis of breast cancer

Comprehensive identification and prioritization of developed artificial intelligence methods for the detection and diagnosis of breast cancer can help to select proper techniques. This study aimed to introduce the best artificial intelligence techniques developed for the detection and diagnosis of breast cancer using microscopic images by fuzzy AHP-TOPSIS techniques.

Volume 112 Issue 2, April 2026

Read the latest issue. It contains the following articles:
The use of bone-modifying agents in early breast cancer: AIOM Guidelines update and perspectives
Delphi Study on the creation of a Committee of patients, caregivers, and representatives of patient associations
The e-BRAVE study: A prospective web-based cohort and biobank of women carriers of BRCA mutations
An indirect approach to identify the healthcare services for thyroid and melanoma cancer patients in Italy: Epicost-2 project
Association of APOC1 levels and nutritional indices with clinicopathological features and prognostic value in patients with DLBCL
Predicting severe toxicity after head-and-neck cancer RT: Validation of the synergist role of a biological marker and dosimetry
Effects of uniportal 3D video-assisted thoracic surgery lobectomy on postoperative pain and immune function in patients with NSCLC
Medication-related jaw osteonecrosis in metastatic RCC treated with VEGFR-TKIs ± IO and bone agents: A real-world analysis

The clinical usefulness of knowing CHRNA5 polymorphism genotype: paving the way for personalized therapy

Tobacco smoking is a leading cause of global mortality, with cessation being the primary prevention strategy. Nicotine addiction has a genetic component; the rs503464 single nucleotide polymorphism (SNP) in the CHRNA5 gene is associated with smoking cessation therapy success.

Nuclear expression of AIRE in lung squamous cell carcinoma correlates with immune microenvironment remodeling and poor prognosis

The autoimmune regulator (AIRE), an atypical transcriptional regulator, exhibits aberrant expression in multiple tumor types. However, its significance in lung squamous cell carcinoma (LUSC) is still uncertain. This study investigated AIRE’s expression, immune microenvironment association, and prognostic value in LUSC.

Quality of life and sexual function after breast conservation surgery and mastectomy without reconstruction in South Indian patients

Breast cancer is a leading malignancy among women worldwide, significantly affecting physical, psychological, and sexual well-being. Surgical options such as breast conservation surgery (BCS) and mastectomy have distinct implications on patients’ quality of life. This study aimed to compare health-related quality of life (HRQoL) and sexual functioning in breast cancer patients undergoing BCS or mastectomy.