We conducted an online survey to investigate oncologists’ clinical practices and views on palliative care at the end of life in the Italian region of Liguria. The survey included 29 items divided into three sections: participant characteristics (n=6), hospital resources and practices (n=11), participant practices and views (n=12).
Read the latest issue. It contains the following articles: PROACT 2.0: A new open-source tool to improve patient-doctor communication in clinical trials; Melanoma and sex hormones: Pathogenesis, progressive disease and response to treatments
Immunogenicity of radiotherapy on bone metastases from prostate adenocarcinoma: What is the future for the combination with radiotherapy/immunotherapy?; Advances in spatial multi-omics in tumors.
Colon cancer imposes a significant burden on global healthcare systems, necessitating efforts to improve oncology care quality and patient outcomes. We studied the correlation between care quality and survival outcomes among colon cancer patients within the Ligurian Oncology Network (Italy).
Read the latest issue. It contains the following articles: The power of art and the powers of adolescents with cancer: Age-specific projects at Italian pediatric oncology centers; Non-neoplastic cells as prognostic biomarkers in diffuse large B-cell lymphoma: A system review and meta-analysis; The digital revolution in pathology: Towards a smarter approach to research and treatment; Novel insights into RB1 in prostate cancer lineage plasticity and drug resistance; North-south differences in incidence and surveillance of cutaneous malignant melanoma in Italy; Dosimetric and NTCP analyses for selecting parotid gland cancer patients for proton therapy; Effect of neoadjuvant chemoradiation on anorectal function assessed with anorectal manometry: A systematic review and meta-analysis; A new era for bladder cancer: Enfortumab vedotin and pembrolizumab milestone approval; In reply to Topkan et al.
The field of cancer research and treatment is rapidly evolving, presenting significant challenges in modern oncology. In response, the Tumori Journal launched a Call for Papers to identify high-quality manuscripts that offer advanced and innovative insights into cancer research and treatment.
Tumour BRCA1/2 sequencing has progressively increased along with the expanding indications for poly(ADP-ribose) polymerase inhibitors. In our study, we investigated the feasibility and outcomes of a workflow for the identification of germline carriers based on tumour sequencing results. Between April 2020 and December 2022, BRCA1/2 tumour testing results from 2020 patients were reviewed. Analysed tumours included: 323 ovarian, 104 breast, 314 pancreas-biliary, 87 prostate, 374 gastrointestinal, 309 lung, and 509 less common histologies.
Colorectal cancer is a worldwide leading cause of death accounting for high-rate mortality. Mutations in the epidermal growth factor receptor and RAS/MAPK pathways, as well as altered methylation genes profiles, have been described as molecular mechanisms promoting and sustaining tumour development and progression.
Quality assurance for stereotactic body radiation treatment requires that isocentric verification be ensured during gantry rotation at various angles. This study examined statistical parameters on Winston-Lutz tests to distinguish the deviation of angles from isocenter during gantry rotation using machine learning.
The aim of this study was to analyze the trend of non-Hodgkin’s lymphoma incidence and mortality in China from 1990 to 2019, along with assessing the effects of age, period, and cohort, as well as to predict future trends. Using data from the Global Burden of Disease Study 2019 we calculated the estimated annual percentage changes in the incidence and mortality of non-Hodgkin’s lymphoma.
Experiences related to pediatric oncology diagnosis cause great imbalances within the family structure. Assessing the frailties and needs of families and children with cancer from a psychosocial perspective is an important step in providing appropriate pediatric psychology care. The aim of this study was to develop an Italian translation of the last version of the Psychosocial Assessment Tool questionnaire (PAT 3.1) and to pilot-test it among pediatric oncological families.