The combination of programmed cell death protein 1 (PD-1) inhibitors and chemotherapy has shown promising results in the treatment of various malignancies. This meta-analysis aims to evaluate the effectiveness and safety of combing PD-1 inhibitor with chemotherapy in patients with advanced NPC.
In the literature, the data about the factors related to the choice of the setting at patient’s first palliative care admission visit are scanty. In fact it seems that the choice between home or hospice care is mainly based on the opinions and needs of patients, families and physicians.
The Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC) is Italy’s first cooperative oncology research group, evolving to conduct academic clinical trials since 1985. With 167 publications and collaborations with national and international partners, GOIRC has significantly impacted clinical practices.
Concurrence of pregnancy and cancer diagnosis is increasingly frequent in Italy. The study aimed to compare women with pregnancy-associated cancers (PACs) to those of childbearing age, focusing on fertility, induced abortion, and miscarriage.
Read the latest issue. It contains the following articles: Hot topics in genitourinary_cancers: A multidisciplinary discussion on state-of-the-art and latest developments among international experts and patient advocacy.
Proton therapy for pediatric malignancies: Indications and challenges focusing on the oncological landscape
Enhanced patient journey associated with improved overall survival in colon cancer patients: A study by the Ligurian Oncology Network
Practices and views about palliative care at the end of life: A survey of oncologists from the Italian region of Liguria
Effect of body mass index on immune checkpoint inhibitor efficacy in patients with advanced cancer
Self-perceived attitudes of Italian oncology nurses towards clinical trial involvement: A cohort observational study.
Fat necrosis after accelerated partial breast irradiation or hypofractionated whole breast irradiation: A case-control study.
High throughput sequencing reveals alterations in B cell receptor repertoires associated with the progression of hepatic cirrhosis to hepatocellular carcinoma
Preoperative chemo-CIRT in Re/BRe pancreatic cancer: Insights from a multicenter prospective phase lI clinical study_(NCT03822936)
Response to lorlatinib rechallenge in a case of ALK-rearranged metastatic NSCLC with a resistance mutation to second generation TKIs
A case series of non-small cell lung cancer patients with EGFR or HER2 exon 20 insertion in Li Fraumeni syndrome
Multiple targets, germline BRCA1 mutation and HRD in a lung cancer patient: Molecular considerations and treatment decision-making
To evaluate short-term (2008–2017) cancer incidence trends in Italy for individuals aged 20-49 years by sex and cancer type. Observational study from population-based data collected by 20 Italian Cancer Registries, covering 33% of the Italian population. The age-standardized incidence rates (ASRs), overall and stratified by area, sex, cancer site or type, and major age groups (i.e., 20-39, 40-49), were computed.
Read the latest issue. This issue contains the Abstract Book for XXVI AIOM National Congress, 8-10 November 2024, Rome (Italy). Guest Editor: Francesco Perrone. This issue includes AIOM Abstract.
The need for predictive factors regarding the response to immune checkpoint inhibitors (ICIs) is increasing. Recent research indicates that an enhanced response to ICIs is associated with a higher body mass index (BMI). This study aims to evaluate the relationship between response to ICIs and BMI in solid tumors.
Hepatocellular carcinoma (HCC) is developed as a consequence of chronic liver cirrhosis, and both diseases are difficult to diagnose and differentiate. Accurate noninvasive biomarkers for HCC and liver cirrhosis are urgently needed. Here we used high-throughput sequencing to characterize the B cell receptor (BCR) repertoires from 36 HCC tumor samples and 10 liver cirrhosis (LC) tissue biopsies to understand the immune alterations during hepatic carcinogenesis.
There is debate about the optimal management of borderline resectable (bRe) and resectable (Re) pancreatic ductal adenocarcinoma (PDAC). Both preclinical and clinical evidence showed that carbon ion radiotherapy (CIRT) produces superior control on radioresistant histologies compared to conventional photon beam radiotherapy (RT).